RBK Projects
Phase 2 Projects (Active)
Projects with a focus on Repair/Regeneration
- AKI Therapeutics
Neil Hukriede (Contact PI), University of Pittsburgh; Alan Davidson, University of Auckland; Mark De Caestecker, Vanderbilt University; Donna Huryn, University of Pittsburgh - Cell-specific Delivery of Novel Therapies to Enhance Glomerular Regeneration and Repair
Stuart Shankland (Contact PI), University of Washington; Benjamin J. Freedman, University of Washington; James M. Roberts, Lumen Bioscience; Oliver Wessely, Cleveland Clinic - Integrating UB collecting systems into hPSC-derived kidney organoids
Kyle McCracken, Cincinnatti Children's - Single-cell Analysis to Promote Kidney Repair
Benjamin D. Humphreys (Contact PI), Washington University in St. Louis; Junhyong Kim, University of Pennsylvania; Andrew McMahon, University of Southern California - Single-nuclei multiome atlas for a mammalian model of kidney regeneration
Elizabeth Nguyen, Seattle Children's - Stepwise developmental mimicry generates proximal tubules in organoids
Nils Lindstrom, University of Southern California
Projects with a Focus on Building
- Building Extracellular Matrix Scaffolds to Induce Nephron Development
Jason A. Wertheim, University of Arizona - Engineering Functional Kidneys
Jennifer Lewis (Contact PI), Harvard University; Ryuji Morizane, Harvard University; Lisa Satlin, Icahn School of Medicine - Functional Renal Engraftment
Iain Drummond (Contact PI), Mount Desert Island Biological Laboratory; Leif Oxburgh, The Rogosin Institute; Denise Marciano, University of Texas, Southwestern - Kidney Microphysiological Analysis Platforms (MAP) to Optimize Function and Model Disease
Joseph Bonventre (Contact PI), Brigham and Women's Hospital; Luke Lee, Brigham and Women's Hospital; Jennifer Lewis, Harvard University - The Synthetic Kidney: A Revolutionary Solution for the Shortage of Kidneys for Transplantation
Zhongwei Li, University of Southern California - Visualizing Vascularization and Cell Interactions in Implanted Organoids
Leif Oxburgh (Contact PI), The Rogosin Institute; Ondine Cleaver, University of Texas, Southwestern; Tom Carroll, University of Texas, Southwestern; Denise Marciano, University of Texas, Southwestern; Bradley Yoder, University of Alabama, Birmingham